Louisville demolition signals next major Midwest AI data center hub

Melissa Palmer

December 17, 2025

Louisville is quietly prepping a large greenfield site for demolition, a classic early signal a hyperscale or large colocation data center is coming.

Nearly 160 acres in southwest Louisville is being cleared, which is enough land for a multi-building campus with serious GPU capacity.

Kentucky’s pitch here is likely power and land: relatively cheap electricity, industrial zoning, and room to expand compared to tighter coastal markets.

If this follows the broader Midwest trend, I expect aggressive power commitments, substation buildout, and pressure on local grids long before the first AI workloads land.

For AI infra buyers, this points to Louisville emerging as another regional cluster where latency-sensitive GPU training and inference can live closer to Midwest enterprises.

The demolition notices and early site work matter more than any official announcement, because they show real capex is already in motion.

This kind of local reporting is where you spot the next wave of AI data center builds before the big vendor press releases drop.

Source: Data centers eye Kentucky amid Midwest boom

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